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Research Highlights
Alaska
Grant:
Contaminants & Infectious Agents: Molecular Approaches
Project:
Outreach - Undergraduate
Grant - Alaska INBRE-2 ARRA Supplement
Grant:
Contaminants & Infectious Agents: Molecular Approaches
Project:
Outreach - Pre-College
Grant - Science Education Partnership Award: Alaska BioPREP
Arkansas
Delaware
Hawaii
Grant:
Institute for Biogenesis Research: COBRE
Project:
The Importance of UDP-Glucuronosyltransferase Enzymes in Pregnancy and Embryogenesis
Artificial Reproductive Technologies can Lead to Aberrations in Placental Steroid Metabolism.
Grant:
Institute for Biogenesis Research: COBRE
Project:
Transposase Mediated Transgenesis and Gene Therapy
Transposase Mediated Transgenesis Leads to Chromosomal Insertion of Introduced Genes in Targetted Organs.
Grant:
Institute for Biogenesis Research: COBRE
Project:
Effects of specific spermatid-expressed Y chromosome genes on sperm function
Artificial Reproductive Technologies can Lead to Aberrations in Placental Steroid Metabolism.
Grant:
Institute for Biogenesis Research: COBRE
Project:
Mechanisms of sex differentiation in mouse fetal germ cells
Male (XY) Primordial Germ Cells can be Induced to become Female Germ Cells with Retinoic Acid.
Idaho
Grant:
Idaho INBRE Program
Project:
Administrative Core
Research Highlights of the Idaho INBRE Program
Grant:
Idaho INBRE Program
Project:
CHARACTERIZATION OF BIOENGINEERED CARTILAGE USING AFM (0021)
Nanomechanical Characterization of Biological Soft Materials Using Scanning Probe Microscopy Techniques
Grant:
Idaho INBRE Program
Project:
SKELETAL BIOLOGY AND ARTHRITIS (0020)
Multiplicity of Col11a1 function during development; structure and signaling
Grant:
Idaho INBRE Program
Project:
INV OF ASTROCYTE CASPASE ACTV & CD40/CD40L SIGNALING INTERACTIONS IN ALZHEIMER’S (0017)
Lack of pathology in a triple transgenic mouse model of Alzheimer’s disease after overexpression of Bcl-2
Grant:
Idaho INBRE Program
Project:
RESEARCH CORE: FACULTY DEVELOPMENT PROGRAM (0004)
Towards Nanometer Scale Devices for Biomedical Applications Using Biomolecular Self-Assembly
Kansas
Grant:
Protein Structure and Function
Project:
Structural Characterization of the Anthrax Toxin Protective Antigen
ResHighlight_Bann
Grant:
Kansas IDeA Network of Biomedical Research Excellence
Project:
THE IMPACT OF DOPAMINE SIGNALING ON FRAGILE X SYNDROME BEHAVIORS
The Impact of Dopamine Signaling on Fragile X Syndrome Behaviors
Grant:
Kansas IDeA Network of Biomedical Research Excellence
Project:
THE ROLE OF GAP JUNCTIONS IN OXIDATIVE NEURODEGENERATION IN CEREBELLUM
The Role of Gap Junctions in Oxidative Neurdegeneration in Cerebellum
Grant:
Kansas IDeA Network of Biomedical Research Excellence
Project:
TAIL MORPHOGENESIS IN ZEBRAFISH
Tail Morphogenesis in Zebrafish
Grant:
Epithelial Function in Health and Disease
Project:
Regulation of Na+ Transport Function by CFTR in Thyroid Epithelial Cells
Regulation of Na+ Transport Function by CFTR in Thyroid Epithelial Cells
Grant:
Epithelial Function in Health and Disease
Project:
Dietary Supplements Protect Retinal Pigment Epithelial Cells from Apoptosis
Dietary Supplements Protect Retinal Pigment Epithelial Cells from Apoptosis
Grant:
Epithelial Function in Health and Disease
Project:
Transepithelial Ion Transport in Mosquito Hindgut Controlled by Peptide Hormone
Transepithelial Ion Transport in Mosquito Hindgut Controlled by Peptide Hormone
Grant:
Epithelial Function in Health and Disease
Project:
BME-UV Monolayers as a Model for the Pharmacokinetics of Xenobiotix in Lactation
BME-UV Monolayers as a Model for the Pharmacokinetics of Xenobiotix in Lactation
Grant:
Center for Cancer Experimental Therapeutics
Project:
Molecular co-crystals: New solid forms for anti-cancer drugs
Highlight Aakeroy FY10
Grant:
Center for Cancer Experimental Therapeutics
Project:
Nanocarrier based intralymphatic imaging and therapy for melanoma
Highlight Cohen FY10
Grant:
Center for Cancer Experimental Therapeutics
Project:
Nanoelectric chip for kinase profiling
Highlight Jun Li FY10
Grant:
Center for Cancer Experimental Therapeutics
Project:
Nanoparticle-based dual gene therapy for lung adenocarcinoma
Highlight Tamura FY10
Kentucky
Grant:
Center of Biomedical Research Excellence in Molecular Basis of Human Disease
Project:
Structural Studies of Neuropilin Signaling
Research Highlights - Vander Kooi
Louisiana
Grant:
Tulane COBRE in Hypertension and Renal Biology
Project:
Tubular Renin-Angiotensin System in Hypertension.
Urinary Aniotensinogen as a Novel Biomarker of the Intrarenal Renin-Angiotensin System Status in Hypertensive patients
Grant:
Tulane COBRE in Hypertension and Renal Biology
Project:
Angiotensin in distal nephron ontogeny
Downregulation of Spry-1, an inhibitor og GDNF-Ret, causes angiotensin II-induced ureteric bud branching
Grant:
Tulane COBRE in Hypertension and Renal Biology
Project:
Intrarenal Angiotensin II generation during Angiotensin II-induced hypertension.
Angiotensin-Converting Enzyme Derived Angiotensin II Formation During Angiotensin II Induced Hypertension
Maine
Grant:
COBRE in Vascular Biology
Project:
Role of Insulin-Like Growth Factor Binding Proteins (IGFBPS) in Angiogenesis
Role of Insulin-Like Growth Factor Binding Proteins (IFGBPS) in Angiogenesis
Grant:
COBRE in Vascular Biology
Project:
The Contribution of SMC to the Pathology of Gastrointestinal Stromal Tumors
The Contribution of SMC to the Pathology of Gastrointestinal Stromal Tumors
Grant:
COBRE in Vascular Biology
Project:
Control of Vascular Fibrosis and Collagen Deposition by Novel Regulator, CTHRC-1
Control of Vascular Fibrosis and Collagen Deposition by Novel Regulator, CTCRC-1 Research Highlight
Grant:
COBRE in Vascular Biology
Project:
Mechanisms of Dyslipidemia in Cardiac Muscle Prior to the Onset of Atherosclerosis
Mechanisms of Dyslipidemia in Cardiac Muscle Prior to the Onset of Atherosclerosis
Grant:
COBRE in Vascular Biology
Project:
Mechanism of Non-Classical Release of the Angiogenesis Regulator, IL1-Alpha
Mechanism of Non-Classical Reslease of the Angiogenisis Regulator, IL1-Alpha
Mississippi
Grant:
COBRE: CENTER FOR PSYCHIATRIC NEUROSCIENCE
Project:
Integrity of the Dorsal Raphe Serotonin System in Alcohol Dependence and Suicide
DECREASED EXPRESSION OF FREUD-1 (TRANSCRIPTIONAL REPRESSOR OF 5-HT1A RECEPTOR) IN PREFRONTAL CORTEX OF MDD SUBJECTS
SCIENCE ADVANCES (Mark Austin)
Grant:
COBRE: CENTER FOR PSYCHIATRIC NEUROSCIENCE
Project:
Glutamate System in Depression
GLUTAMATE RECEPTORS: POTENTIAL BIOMARKERS FOR DEPRESSION?
SCIENCE ADVANCES (Beata Karolewicz)
Grant:
COBRE: CENTER FOR PSYCHIATRIC NEUROSCIENCE
Project:
Vascular and Cellular Pathology in Depression
SCIENCE ADVANCES (Grazyna Rajkowska)
Grant:
COBRE: CENTER FOR PSYCHIATRIC NEUROSCIENCE
Project:
Serotonin Related Transcription Factors in Animal Stress Models Related to Depression
SCIENCE ADVANCES (Abiye Iyo)
Grant:
COBRE: CENTER FOR PSYCHIATRIC NEUROSCIENCE
Project:
The Role of Glyceraldehyde-3-phosphate Dehydrogenase in Depression and Alcoholism
SCIENCE ADVANCES (Xiaoming Ou)
Grant:
COBRE: CENTER FOR PSYCHIATRIC NEUROSCIENCE
Project:
Estrogen Receptor Splice Variants and Menopause-Related Depression
SCIENCE ADVANCES (Junming Wang)
Grant:
COBRE: CENTER FOR PSYCHIATRIC NEUROSCIENCE
Project:
(1) Postmortem Human Brain Collection Core
SCIENCE ADVANCE (Brain Core)
Montana
Nebraska
Grant:
Nebraska Center for Virology
Project:
Characterization of HIV-1 Preintegration Complex Assembly and Nuclear Transport
Belshan Part 5 2009
Grant:
Nebraska Center for Virology
Project:
Immune Modulation and Restoration in HIV-1 Infection
Gorantha Research Highlights
Grant:
Nebraska Center for Virology
Project:
Longitudinal Analysis of HIV-1 Clade C Fitness
Zhang Part 5 Research Highlights
Nevada
New Hampshire
Grant:
Center for Molecular, Cellular, and Translational Immunological Research
Project:
The Impact of IRF-3- dependent mechanisms upon the replication and virulence of HSV
Research Highlights The impact of IRF-3- dependent mechanisms upon the replication and virulence of HSV
Grant:
Center for Molecular, Cellular, and Translational Immunological Research
Project:
Peripheral Blood Mononuclear Cell (PBMC) Gene Expression in metastatic Renal Cell Carcinoma (RCC) Patients
Research Highlights Peripheral blood mononuclear cell (PBMC) gene expression in Metastatic renal cell
Research Highlights Peripheral blood mononuclear cell (PBMC) gene expression in
Research Highlights Peripheral blood mononuclear cell (PBMC) gene expression in Metastatic renal cell
Grant:
Center for Molecular, Cellular, and Translational Immunological Research
Project:
Molecular Biology Core/Immune Monitoring Laboratory
Research Highlights Molecular Biology Core
Research Highlights Molecular Biology Core
Grant:
Center for Molecular, Cellular, and Translational Immunological Research
Project:
Transgenic Mice
Research Highlights Transgenic Mice
Grant:
Center for Molecular, Cellular, and Translational Immunological Research
Project:
Informatics Support Core
Informatics Core Research Highlights
Grant:
Center for Molecular, Cellular, and Translational Immunological Research
Project:
Scavenger receptor function in chaperone-elicited adaptive immune responses
Research Highlights Scavenger receptor function in chaperone-elicited adaptive immune
Grant:
Center for Molecular, Cellular, and Translational Immunological Research
Project:
Vascular Leukocytes: Basic immunobiology and functional plasticity
Research Highlights: Vascular leukocytes: Basic immunobiology and functional plasticity
New Mexico
Grant:
COBRE CENTER FOR EVOLUTIONARY AND THEORETICAL IMMUNOLOGY
Project:
Predicting Viral Dynamics, Immune Response and Epidemic Spread of Multi-host Pathogens
Essay in the Being Human Series, Engineering: World Wide Ebb
Grant:
New Mexico IDeA Networks of Biomedical Research Excellence
Project:
Multi-drug Resistance in Staphylococcus aureus Clinical Isolates
Presence of Multidrug-Resistant Enteric Bacteria in Dairy Farm Topsoil
Grant:
New Mexico IDeA Networks of Biomedical Research Excellence
Project:
Development of novel small molecule inhibitors of Aurora B kinase signaling
Bisphenol A Directly Targets Tubulin to Disrupt Spindle Organization in Embryonic and Somatic Cells
North Dakota
Grant:
Pathophysiological Signaling in Neurodegenerative Disorders
Project:
Cholesterol, Caffeine and Alzheimer Disease-Like Pathology in Rabbit Brain
Cholesterol, Caffeine and Alzheimer Disease-Like Pathology in Rabbit Brain Highlights
Grant:
Pathophysiological Signaling in Neurodegenerative Disorders
Project:
Tachykinin Modulation of Epilepsy
Tachykinin Modulation of Epilepsy Highlights
Grant:
Pathophysiological Signaling in Neurodegenerative Disorders
Project:
Lipid-Mediated Signaling and Neuroinflammation
Lipid-Mediated Signaling and Neuroinflammation Highlights
Grant:
Pathophysiological Signaling in Neurodegenerative Disorders
Project:
TRPC1, Calcium and Parkinson's Disease
TRPC1, Calcium and Parkinson's Disease Highlights
Grant:
Pathophysiological Signaling in Neurodegenerative Disorders
Project:
CNTF Promotes Neuronal Survival and Axonal Sprouting
CNTF Promotes Neuronal Survival and Axonal Sprouting Highlights
Grant:
New Strategies for Targeting Protease in Disease
Project:
EPIGENETIC REGULATION OF VASOACTIVE INTESTINAL PEPTIDE
How Ikaros (IK) bidirectionally and epigenetically modulates transcriptional expression
Grant:
New Strategies for Targeting Protease in Disease
Project:
MMP-9 IN APOPTOSIS OF PROSTATE CANCER CELLS
How MMP-9 regulates apoptosis in prostate cancer cells
Grant:
New Strategies for Targeting Protease in Disease
Project:
MMP-2 IN ASTHMA
Airway remodeling in allergic asthma
Grant:
New Strategies for Targeting Protease in Disease
Project:
The role of MMPs in myostatin activation in skeletal muscle of obese and non-obese mice
Strains of mice exhibit varying responses to environmental factors such as dietary intake
Oklahoma
Grant:
Mentoring Vision Research In Oklahoma
Project:
EGFR-MEDIATED CORNEAL EPITHELIAL WOUND HEALING
Research Highlights - Ceresa
Grant:
Mentoring Vision Research In Oklahoma
Project:
STRUCTURE AND FUNCTION RELATIONSHIP OF CONE CYCLIC NUCLEOTIDE-GATED CHANNEL
Research Highlights - Ding
Grant:
Mentoring Vision Research In Oklahoma
Project:
IN VIVO ROLE OF CAVEOLIN-1 IN MODULATING PHOTORECEPTOR FUNCTION
Research Highlights - Elliott
Grant:
Mentoring Vision Research In Oklahoma
Project:
PHOTORECEPTOR RETINOL DEHYDROGENASES AND VISION
Research Highlights - Kasus-Jacobi
Grant:
Mentoring Vision Research In Oklahoma
Project:
SPHINGOLIPID METABOLISM IN THE RETINA
Research Highlights - Mandal
Puerto Rico
Rhode Island
Grant:
COBRE for Skeletal Health and Repair
Project:
RI COBRE: Assessment of Chondroprotection in ACL Injuries (0007)
Research Highlights_0007
Grant:
COBRE for Skeletal Health and Repair
Project:
RI COBRE: Endocrine and Nutritional Control of Long Bone Growth (0005)
Research Highlights_0005
Grant:
COBRE for Skeletal Health and Repair
Project:
RI COBRE: Mechanisms of Angiogenesis in Chondrosarcoma (0006)
Research Highlights_0006
Grant:
New Approaches to Tissue Repair
Project:
Development of bispecific antibodies to facilitate tissue repair cell recruitment
Bispecific antibodies
Grant:
New Approaches to Tissue Repair
Project:
Use of stem cells in wound healing
Stem Cells Wound Healing
Grant:
New Approaches to Tissue Repair
Project:
Bone marrow subpopulations to repair human islet injury and support its longevity
Islet Cells
Grant:
COBRE for Perinatal Biology
Project:
Neonatal Candidiasis and Immune Compromise during Development
WIH COBRE Project I Highlights
WIH COBRE Project I
Grant:
Rhode Island Network for Molecular Toxicology
Project:
Fate of Mercury Contaminants in Narragansett Bay, Rhode Island
Research Highlight - Taylor
Grant:
Rhode Island Network for Molecular Toxicology
Project:
Identification of New Drugs Against Amebiasis by Targeting Protozoan Anaerobic Metabolism
Research Highlight - Espinosa
Grant:
Rhode Island Network for Molecular Toxicology
Project:
Characterization of Pyrethroids on Human Voltage-Sensitive Calcium Channels
Research Highlight - Symington
South Carolina
South Dakota
Vermont
Grant:
Center for Neuroscience Excellence
Project:
Project 2 - Expression of the AMPA Receptor Subunit GluR2 in Chick Lumbar Motoneurons
Project 2 Research Highlights
Grant:
Center for Neuroscience Excellence
Project:
Project 3 - Adult Bone Marrow Stem Cells for CNS Repair
Project 3 Research Highlights
Grant:
Center for Neuroscience Excellence
Project:
Project 4 - Role of Dipeptidyl Peptidase IV in Peripheral Neurogenesis and Neuroblastomas
Project 4 Research Highlights
Grant:
Vermont Genetics Network - Vermont INBRE
Project:
Baseline Airway Mechanical Function and Airway Function During Exercise in Asthma
Research Highlights
Grant:
Vermont Genetics Network - Vermont INBRE
Project:
Psychomotor Stimulant Induced Sensitization of Impulsive Behavior
Research Highlights
Grant:
Vermont Genetics Network - Vermont INBRE
Project:
The Molecular Mechanism of Ethylene Regulation of Photoperiodic Plant Flowering
Research Highlights
West Virginia
Wyoming
